The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.a

DRES syndrome - DRESS-like reaction

Publications

Jeremic I, Vujasinovic-Stupar N, Terzic T, Damjanov N, Nikolic M, Bonaci-Nikolic B

Fatal sulfasalazine-induced eosinophilic myocarditis in a patient with periodic fever syndrome.

Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2015;24;195-7 — 2015 — 195-7

Pirklbauer M, Gruber J

[DRESS syndrome following sulfasalazine treatment].

Zeitschrift fur Rheumatologie 2014 Mar;73;180-3 — 2014 Mar — 180-3

Giri PP, Roy S, Bhattyacharya S, Pal P, Dhar S

Dress syndrome with sepsis, acute respiratory distress syndrome and pneumomediastinum.

Indian journal of dermatology 2011 Nov;56;763-5 — 2011 Nov — 763-5

Tung Y, Escutia B, Blanes M, Navarrro M, Pujol C

[Sulfasalazine-induced hypersensitivity syndrome associated with human herpesvirus 6 reactivation and induction of antiphospholipid syndrome].

Actas dermo-sifiliograficas 2011 Sep;102;537-40 — 2011 Sep — 537-40

Chaabane A, Aouam K, Ben Fredj N, A Boughattas N

[DRESS syndrome: 11 case reports and a literature review].

Therapie 2010 Nov-Dec;65;543-50 — 2010 Nov-Dec — 543-50

Piñana E, Lei SH, Merino R, Melgosa M, De La Vega R, Gonzales-Obeso E, Ramírez E, Borobia A, Carcas A

DRESS-syndrome on sulfasalazine and naproxen treatment for juvenile idiopathic arthritis and reactivation of human herpevirus 6 in an 11-year-old Caucasian boy.

Journal of clinical pharmacy and therapeutics 2010 Jun;35;365-70 — 2010 Jun — 365-70

Augusto JF, Sayegh J, Simon A, Croue A, Chennebault JM, Cousin M, Subra JF

A case of sulphasalazine-induced DRESS syndrome with delayed acute interstitial nephritis.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009 Sep;24;2940-2 — 2009 Sep — 2940-2

Aquino RT, Vergueiro CS, Magliari ME, de Freitas TH

Sulfasalazine-induced DRESS syndrome (Drug Rash with Eosinophilia and Systemic Symptoms).

Sao Paulo medical journal = Revista paulista de medicina 2008 Jul;126;225-6 — 2008 Jul — 225-6