The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pneumonitis (interstitial lung disease/ILD)
Publications
Late onset interstitial pneumonia induced by bepridil: A case report.
Journal of arrhythmia 2015 Feb;31;47-9 — 2015 Feb — 47-9
Yamasaki K, Yatera K, Noguchi S, Oda K, Akata K, Nishida C, Kawanami T, Kawanami Y, Ishimoto H, Ono S, Wakuta Y, Mukae H
Incidence and outcomes of bepridil-induced interstitial pneumonia.
Respiratory medicine 2013 Dec;107;2088-91 — 2013 Dec — 2088-91
Gradual progression of interstitial pneumonia induced by bepridil.
Internal medicine (Tokyo, Japan) 2009;48;2033-5 — 2009 — 2033-5
Two patients with bepridil-induced interstitial pneumonia.
Circulation journal : official journal of the Japanese Circulation Society 2009 Jul;73;1352-5 — 2009 Jul — 1352-5
Okubo F, Ando M, Ashihara Y, Okubo T, Nishitake T, Ito T, Matsuno O, Fukami T, Miyazaki E, Kumamoto T
[A case of drug-induced pneumonitis due to bepridil].
Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 2006 Jan;44;17-21 — 2006 Jan — 17-21
A case of bepridil induced interstitial pneumonitis.
Heart (British Cardiac Society) 2003 Dec;89;1415 — 2003 Dec — 1415