The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIX.j

Eosinophilic granulomatosis with polyangiitis (Churg-Strauss)

Publications

Calapai G, Casciaro M, Miroddi M, Calapai F, Navarra M, Gangemi S

Montelukast-induced adverse drug reactions: a review of case reports in the literature.

Pharmacology 2014;94;60-70 — 2014 — 60-70

Man MA, Alexandrescu D, Pop M, Trofor A

Churg Strauss syndrome associated with montelukast--case report.

Pneumologia (Bucharest, Romania) 2012 Apr-Jun;61;113-6 — 2012 Apr-Jun — 113-6

Uyar M, Elbek O, Bak?r K, Kibar Y, Bayram N, Dikensoy Ö

Churg-Strauss syndrome related to montelukast.

Tuberkuloz ve toraks 2012;60;56-8 — 2012 — 56-8

Anar C, Ünsal I, Ozanturk ME, Halilçolar H, Yucel N

A case of Churg-Strauss syndrome treated with montelukast.

Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2012;21;186-9 — 2012 — 186-9

Kanda T, Tanio H, Wu C, Nishihara H, Nogaki F, Ono T

Churg-Strauss syndrome with severe granulomatous angiitis and crescentic glomerulonephritis, which developed during therapy with a leukotriene receptor antagonist.

Clinical and experimental nephrology 2010 Dec;14;602-7 — 2010 Dec — 602-7

Bibby S, Healy B, Steele R, Kumareswaran K, Nelson H, Beasley R

Association between leukotriene receptor antagonist therapy and Churg-Strauss syndrome: an analysis of the FDA AERS database.

Thorax 2010 Feb;65;132-8 — 2010 Feb — 132-8

Kaliterna DM, Perkovi? D, Radi? M

Churg-Strauss syndrome associated with montelukast therapy.

The Journal of asthma : official journal of the Association for the Care of Asthma 2009 Aug;46;604-5 — 2009 Aug — 604-5

Conen D, Leuppi J, Bubendorf L, Ronsdorf A, Tamm M, Hauser T

Montelukast and Churg-Strauss syndrome.

Swiss medical weekly 2004 Jun 26;134;377-80 — 2004 Jun 26 — 377-80

Guilpain P, Viallard JF, Lagarde P, Cohen P, Kambouchner M, Pellegrin JL, Guillevin L

Churg-Strauss syndrome in two patients receiving montelukast.

Rheumatology (Oxford, England) 2002 May;41;535-9 — 2002 May — 535-9

Mukhopadhyay A, Stanley NN

Churg-Strauss syndrome associated with montelukast.

Postgraduate medical journal 2001 Jun;77;390-1 — 2001 Jun — 390-1