The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Diaphragm/inspiratory muscle weakness/paralysis (w/wo ARF)
Publications
[Severe respiratory failure and neuromuscular blockade after administration of colimycin].
Medicina intensiva 2015 Oct;39;448-9 — 2015 Oct — 448-9
Sudden respiratory muscle paralysis and apnea in a patient infected with multidrug-resistant Pseudomonas aeruginosa treated with intravenous colistin.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2013 May;17;e357 — 2013 May — e357
Intravenous and inhalational colistin-induced respiratory failure.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2010 Mar 15;50;e38-40 — 2010 Mar 15 — e38-40
Adverse effects of drugs on the respiratory muscles.
Clinics in chest medicine 1990 Mar;11;177-89 — 1990 Mar — 177-89