The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pleural thickening - Fibrothorax
Publications
Pleuropulmonary Toxicity of Another Anti-Parkinson's Drug: Cabergoline.
The open respiratory medicine journal 2009 Jun 05;3;90-3 — 2009 Jun 05 — 90-3
Cardiac and noncardiac fibrotic reactions caused by ergot-and nonergot-derived dopamine agonists.
Movement disorders : official journal of the Movement Disorder Society 2009 Jan 15;24;129-33 — 2009 Jan 15 — 129-33
Fibrosis associated with dopamine agonist therapy in Parkinson's disease.
Clinical neuropharmacology 2003 May-Jun;26;109-11 — 2003 May-Jun — 109-11