The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

IV.ab

Cough (lone)

Publications

Aquilina C, Mularczyk M, Lucas F, Viraben R

Unusual clinical presentation of hypersensitivity reaction to abacavir.

AIDS (London, England) 2003 Nov 07;17;2403-4 — 2003 Nov 07 — 2403-4

Hetherington S, McGuirk S, Powell G, Cutrell A, Naderer O, Spreen B, Lafon S, Pearce G, Steel H

Hypersensitivity reactions during therapy with the nucleoside reverse transcriptase inhibitor abacavir.

Clinical therapeutics 2001 Oct;23;1603-14 — 2001 Oct — 1603-14