The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pericardial effusion (w/wo tamponade)
Publications
Ferrusquía J, Pérez-Martínez I, Gómez de la Torre R, Fernández-Almira ML, de Francisco R, Rodrigo L, Riestra S
Gastroenterology case report of mesalazine-induced cardiopulmonary hypersensitivity.
World journal of gastroenterology 2015 Apr 07;21;4069-77 — 2015 Apr 07 — 4069-77
Drug-induced pericarditis mimicking Brugada syndrome.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2007 Jan;9;66-8 — 2007 Jan — 66-8
Possible mesalamine-induced pericarditis: case report and literature review.
Pharmacotherapy 2002 Mar;22;391-4 — 2002 Mar — 391-4
Pleuropericarditis related to the use of mesalamine.
Digestive diseases and sciences 1996 Mar;41;624-6 — 1996 Mar — 624-6
[Ulcerative colitis and pericarditis. The role of mesalazine hypersensitivity].
Revue medicale de la Suisse romande 1995 Nov;115;935-8 — 1995 Nov — 935-8
[Recurrent pericarditis induced by mesalazine (5-ASA)].
Therapie 1994 Jul-Aug;49;359-61 — 1994 Jul-Aug — 359-61