The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pleural effusion (uni- or bilateral) (can accompany DI-LDs)
Publications
Mesalamine-associated pleural effusion with pulmonary infiltration.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 1998 Nov 01;55;2304-5 — 1998 Nov 01 — 2304-5
Mesalazine toxicity.
BMJ (Clinical research ed.) 1994 Feb 19;308;533-4 — 1994 Feb 19 — 533-4