The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pneumonitis (interstitial lung disease/ILD)
Publications
Mesalazine-induced Hypersensitivity Pneumonitis.
European journal of case reports in internal medicine 2021;8;002194 — 2021 — 002194
Can a drug-induced pulmonary hypersensitivity reaction be dose-dependent? A case with mesalamine.
The Mount Sinai journal of medicine, New York 2001 Nov;68;389-95 — 2001 Nov — 389-95
Lung disease associated with orally administered mesalamine for ulcerative colitis.
Chest 1992 May;101;1469-71 — 1992 May — 1469-71