The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

II.a

Pulmonary edema, noncardiogenic (NCPE)

Publications

Yang Z, Wu W, Yu Y, Liu H

Atosiban-induced acute pulmonary edema: A rare but severe complication of tocolysis.

Heliyon. 2023;9(5):e15829

Chen Y, Jiang CY, Deng ZW, Duan ZX, Shu YL, Zhou JL

A case of severe non-cardiogenic pulmonary edema in a woman treated with atosiban for preterm labor.

European review for medical and pharmacological sciences. 2023;27(4):1305-1310

Nijs K, Nulens K, Dubois J, Van de Velde M, Stessel B

The combination of corticosteroid and tocolytic therapy in a preeclamptic patient is a risk factor for the development of acute pulmonary oedema.

International journal of obstetric anesthesia. 2018;34:113-114

Hourbracq M, Mattuizzi A, Madar H, Sentilhes L

Non-cardiogenic pulmonary edema in a woman treated with atosiban for preterm labor.

European journal of obstetrics, gynecology, and reproductive biology. 2017;219:132-133

Fernández A, Domínguez D, Delgado L

Severe non-cardiogenic pulmonary oedema secondary to atosiban and steroids.

International journal of obstetric anesthesia. 2011;20(2):189-90

Donders GG, Van Keirsbilck J, De Roo T, Schreven L, Hanssens M

Non-cardiogenic lung edema in a woman treated with atosiban for preterm labor.

Journal of perinatal medicine. 2008;36(5):455-7