The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XII.ag

Bradycardia

Publications

Kanagala SG, Dholiya H, Jhajj P, Patel MA, Gupta V, Gupta S, Wu SI, Jain R

Remdesivir-Induced Bradycardia.

Southern medical journal. 2023;116(3):317-320

Adamo G, Amata M, Cannizzaro N, Chessari C, Sapienza GM, Capizzi GM, Battaglia S, Benfante A, Scichilone N

Transient asymptomatic bradycardia and remdesivir in COVID-19 patients.

Minerva medica. 2023;114(4):463-468

Maheshwari M, Athiraman H

Bradycardia Related to Remdesivir During COVID-19: Persistent or Permanent?

Cureus. 2021;13(11):e19919

Attena E, Albani S, Maraolo AE, Mollica M, De Rosa A, Pisapia R, Fiorentino G, Parrella R, Severino S, Russo V

Remdesivir-Induced Bradycardia in COVID-19: A Single Center Prospective Study.

Circulation. Arrhythmia and electrophysiology. 2021;14(7):e009811