The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.b

Pneumonitis (interstitial lung disease/ILD)

Publications

Atkins C, Maheswaran T, Rushbrook S, Kamath A

Lansoprazole-induced acute lung and liver injury: a case report.

International journal of clinical pharmacology and therapeutics 2014 Dec;52;1102-4 — 2014 Dec — 1102-4

Hwang KW, Woo OH, Yong HS, Shin BK, Shim JJ, Kang EY

Reversible lansoprazole-induced interstitial lung disease showing improvement after drug cessation.

Korean journal of radiology 2008 Mar-Apr;9;175-8 — 2008 Mar-Apr — 175-8