The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pneumonitis (interstitial lung disease/ILD)
Publications
Hypersensitivity pneumonitis associated with azathioprine therapy in a patient with granulomatosis with polyangiitis.
Rheumatology international 2016 Jul;36;1027-32 — 2016 Jul — 1027-32
Azathioprine induced pneumonitis in a patient with ulcerative colitis.
Journal of Crohn's & colitis 2009 Dec;3;309-12 — 2009 Dec — 309-12
[Azathioprine-associated interstitial pneumonitis].
Orvosi hetilap 2006 Feb 12;147;259-62 — 2006 Feb 12 — 259-62
Azathioprine-induced lung toxicity and efficacy of cyclosporin A in a young girl with type 2 autoimmune hepatitis.
Journal of pediatric gastroenterology and nutrition 2000 Aug;31;190-2 — 2000 Aug — 190-2
Azathioprine-associated pulmonary dysfunction.
Chest 1983 Apr;83;696-8 — 1983 Apr — 696-8
Interstitial pneumonitis secondary to azathioprine in a renal transplant patient.
Thorax 1983 Dec;38;951-2 — 1983 Dec — 951-2
Interstitial pneumonitis associated with azathioprine therapy.
American journal of clinical pathology 1978 Feb;69;181-5 — 1978 Feb — 181-5