The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLV.e

Hemothorax - Serosanguineous pleural effusion

Publications

Heneghan NR, Pup C, Koulidis K, Rushton A

Thoracic adverse events following spinal manipulative therapy: a systematic review and narrative synthesis.

The Journal of manual & manipulative therapy 2020 Mar 09;;1-12 — 2020 Mar 09 — 1-12

Struewer J, Frangen TM, Ziring E, Hinterseher U, Kiriazidis I

Massive hematothorax after thoracic spinal manipulation for acute thoracolumbar pain.

Orthopedic reviews 2013;5;e27 — 2013 — e27