The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LVIII.d

Path: Organizing pneumonia (OP/BOOP) pattern (see also Id)

Publications

Wu Y, Chen H, Guan J, Zhang K, Wu W, Li X, Zhang J

Organizing pneumonia in ALK+ lung adenocarcinoma treated with ceritinib: A case report and literature review.

Medicine 2021 Jul 02;100;e26449 — 2021 Jul 02 — e26449

Lim SM, An HJ, Park HS, Kwon HJ, Y Kim E, Hur J, Moon YW

Organizing pneumonia resembling disease progression in a non-small-cell lung cancer patient receiving ceritinib: A case report.

Medicine 2018 Aug;97;e11646 — 2018 Aug — e11646