The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLV.a

Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

Publications

Anees M, Chiu K, Goertzen S, Jimenez CA, Faiz SA

Docetaxel-Induced Serositis Mimicking Malignant Pleural Effusion.

Clinical case reports 2026 Jun;14;e72768 — 2026 Jun

Park SI, Jeon WH, Jeung HJ, Kim GC, Kim DK, Sim YJ

Clinical features of docetaxel chemotherapy-related lymphedema.

Lymphatic research and biology 2014 Sep;12;197-202 — 2014 Sep — 197-202

Tamiya A, Naito T, Miura S, Morii S, Tsuya A, Nakamura Y, Kaira K, Murakami H, Takahashi T, Yamamoto N, Endo M

Interstitial lung disease associated with docetaxel in patients with advanced non-small cell lung cancer.

Anticancer research 2012 Mar;32;1103-6 — 2012 Mar — 1103-6