The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

IV.n

Obstructive airway dysfunction (see also IVc, XVx)

Publications

Mitchell C, Lawson R

Screening Heroin Smokers' Lung Function at Community Care Clinics.

Chest. 2020;157(3):484-486

Nightingale R, Mortimer K, Giorgi E, Walker PP, Stolbrink M, Byrne T, Marwood K, Morrison-Griffiths S, Renwick S, Rylance J, Burhan H

Screening Heroin Smokers Attending Community Drug Clinics for Change in Lung Function: A Cohort Study.

Chest. 2020;157(3):558-565

Tashkin DP

Heroin Smoking and COPD: A Case for Targeted Screening Spirometry.

Chest. 2019;155(2):247-248

Burhan H, Young R, Byrne T, Peat R, Furlong J, Renwick S, Elkin T, Oelbaum S, Walker PP

Screening Heroin Smokers Attending Community Drug Services for COPD.

Chest. 2019;155(2):279-287