The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Diffuse pulmonary calcification (calciphylaxis)
Publications
Vitamin D intoxication with metastatic calcification.
Journal of the American Medical Association. 1946;130:1208-15
Vitamin D intoxication with metastatic calcification; fatal case in an adult with autopsy.
Proceedings. American Federation for Clinical Research. 1945;2:53
Vitamin D poisoning with metastatic calcification; report of a case and review of the mechanism of intoxication.
The American journal of medicine. 1953;14(1):116-23
[Pulmonary calcification in vitamin D poisoning in an infant].
La Pediatria medica e chirurgica : Medical and surgical pediatrics. 1988;10(5):541-2