The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.c

Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

Publications

Oh S, Cha SI, Kim H, Kim M, Choi SH, Seo H, Park TI

A case of venlafaxine-induced interstitial lung disease.

Tuberculosis and respiratory diseases. 2014;77(2):81-4

Tsigkaropoulou E, Hatzilia D, Rizos E, Christodoulou C, Loukides S, Papiris S, Lykouras L

Venlafaxine-induced acute eosinophilic pneumonia.

General hospital psychiatry. 2011;33(4):411.e7-9

Oermann CM, Panesar KS, Langston C, Larsen GL, Menendez AA, Schofield DE, Cosio C, Fan LL

Pulmonary infiltrates with eosinophilia syndromes in children.

The Journal of pediatrics. 2000;136(3):351-8

Fleisch MC, Blauer F, Gubler JG, Kuhn M, Scherer TA

Eosinophilic pneumonia and respiratory failure associated with venlafaxine treatment.

The European respiratory journal. 2000;15(1):205-8