The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Eosinophilic pleural effusion
Publications
Divalproex sodium-induced eosinophilic pleural effusion.
American journal of therapeutics 2009 Nov-Dec;16;593-5 — 2009 Nov-Dec — 593-5
Sodium valproate as a cause of recurrent transudative pleural effusion: a case report.
Journal of medical case reports 2009 Feb 09;3;51 — 2009 Feb 09 — 51
Valproic acid-induced eosinophilic pleural effusion: a case report and review of the literature.
The American journal of the medical sciences 2007 May;333;290-2 — 2007 May — 290-2
Eosinophilic pleural effusion secondary to treatment with valproic acid.
Actas espanolas de psiquiatria 2005 Nov-Dec;33;401-2 — 2005 Nov-Dec — 401-2
Valproic acid-induced eosinophilic pleural effusion.
Southern medical journal 2003 Aug;96;803-6 — 2003 Aug — 803-6
Pleural fluid eosinophilia with combined pharmacotherapy.
Psychosomatics 2003 Sep-Oct;44;436-7 — 2003 Sep-Oct — 436-7
Eosinophilic pleural effusion associated with valproic acid administration.
Southern medical journal 1995 Aug;88;881-2 — 1995 Aug — 881-2