The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLVI.b

Pulmonary arterial hypertension

Publications

Kay JM

Dietary pulmonary hypertension.

Thorax 1994;49 Suppl;S33-8 — 1994 — S33-8

Tazelaar HD, Myers JL, Drage CW, King TE, Aguayo S, Colby TV

Pulmonary disease associated with L-tryptophan-induced eosinophilic myalgia syndrome. Clinical and pathologic features.

Chest 1990 May;97;1032-6 — 1990 May — 1032-6

Yakovlevitch M, Siegel M, Hoch DH, Rutlen DL

Pulmonary hypertension in a patient with tryptophan-induced eosinophilia-myalgia syndrome.

The American journal of medicine 1991 Feb;90;272-3 — 1991 Feb — 272-3

Campagna AC, Blanc PD, Criswell LA, Clarke D, Sack KE, Gold WM, Golden JA

Pulmonary manifestations of the eosinophilia-myalgia syndrome associated with tryptophan ingestion.

Chest 1992 May;101;1274-81 — 1992 May — 1274-81