The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.c

Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

Publications

Yamamoto T, Tanida T, Ueta E, Kimura T, Doi S, Osaki T

Pulmonary infiltration with eosinophilia (PIE) syndrome induced by antibiotics, PIPC and TFLX during cancer treatment.

Oral oncology 2001 Jul;37;471-5 — 2001 Jul — 471-5

Kimura N, Miyazaki E, Matsuno O, Abe Y, Tsuda T

[Drug-induced pneumonitis with eosinophilic infiltration due to tosufloxacin tosilate].

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 1998 Jul;36;618-22 — 1998 Jul — 618-22