The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pneumonitis (interstitial lung disease/ILD)
Publications
Nakamura R, Imamura T, Onitsuka H, Mishima K, Ishikawa T, Nagoshi T, Fujiura Y, Date H, Maeno M, Matsuo T, Koiwaya Y, Eto T
Interstitial pneumonia induced by ticlopidine.
Circulation journal : official journal of the Japanese Circulation Society 2002 Aug;66;773-6 — 2002 Aug — 773-6
Ticlopidine-induced interstitial pulmonary disease: a case report.
Chest 2001 Jun;119;1963-5 — 2001 Jun — 1963-5