The Drug-Induced Respiratory Disease Website and App

Tetrachloroethylene - Perchlorethylene (C2Cl4)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.a

Pneumonitis (interstitial lung disease/ILD)

Publications

Jobard S, Chaigne B, Marchand-Adam S, Lasfargues G, Diot E

Organizing pneumonia and occupational and environmental risk factors: a case-control study.

International archives of occupational and environmental health 2017 Nov;90;865-871 — 2017 Nov — 865-871

Tanios MA, El Gamal H, Rosenberg BJ, Hassoun PM

Can we still miss tetrachloroethylene-induced lung disease? The emperor returns in new clothes.

Respiration; international review of thoracic diseases 2004 Nov-Dec;71;642-5 — 2004 Nov-Dec — 642-5