The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.c

Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

Publications

Tsigkaropoulou E, Hatzilia D, Rizos E, Christodoulou C, Loukides S, Papiris S, Lykouras L

Venlafaxine-induced acute eosinophilic pneumonia.

General hospital psychiatry 2011 Jul-Aug;33;411.e7-9 — 2011 Jul-Aug — 411.e7-9

WILSON IC, GAMBILL JM, SANDIFER MG

Loeffler's syndrome occurring during imipramine therapy.

The American journal of psychiatry 1963 Mar;119;892-3 — 1963 Mar — 892-3