The Drug-Induced Respiratory Disease Website and App

Palytoxin (a potent zoanthid marine coral toxin)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

II.b

ARDS - Acute lung injury

Publications

Thakur LK, Jha KK

Palytoxin-induced acute respiratory failure.

Respiratory medicine case reports. 2017;20:4-6

Sud P, Su MK, Greller HA, Majlesi N, Gupta A

Case series: inhaled coral vapor--toxicity in a tank.

Journal of medical toxicology : official journal of the American College of Medical Toxicology. 2013;9(3):282-6

Makowski EL, Schneider JM, Tsoulos NG, Colwill JR, Battaglia FC, Meschia G

Cerebral blood flow, oxygen consumption, and glucose utilization of fetal lambs in utero.

American journal of obstetrics and gynecology. 1972;114(3):292-303