The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.af

Thrombotic microangiopathy

Publications

Reig Mezquida JP, Jover AS, Ansótegui Barrera E, Escrivá Peiró J, Pastor Colom MD, Pastor Guillem J

Thrombotic microangiopathy associated with tacrolimus in lung transplantation.

Archivos de bronconeumologia. 2015;51(5):e23-4

Boyer NL, Niven A, Edelman J

Tacrolimus-associated thrombotic microangiopathy in a lung transplant recipient.

BMJ case reports. 2013;2013