The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

II.b

ARDS - Acute lung injury

Publications

Alhadi S, Tiwari A, Vohra R, Gerona R, Acharya J, Bilello K

High times, low sats: diffuse pulmonary infiltrates associated with chronic synthetic cannabinoid use.

Journal of medical toxicology : official journal of the American College of Medical Toxicology 2013 Jun;9;199-206 — 2013 Jun — 199-206

Gilbert CR, Baram M, Cavarocchi NC

"Smoking wet": respiratory failure related to smoking tainted marijuana cigarettes.

Texas Heart Institute journal 2013;40;64-7 — 2013 — 64-7