The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XX.a

Respiratory tract infection incl. pneumonia

Publications

Rusta-Sallehy S, Gooderham M, Papp K

Brodalumab: A Review of Safety.

Skin therapy letter 2018 03;23;1-3 — 2018 03 — 1-3

Farahnik B, Beroukhim K, Abrouk M, Nakamura M, Zhu TH, Singh R, Lee K, Bhutani T, Koo J

Brodalumab for the Treatment of Psoriasis: A Review of Phase III Trials.

Dermatology and therapy 2016 Jun;6;111-24 — 2016 Jun — 111-24