The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLI.a

Pulmonary edema, noncardiogenic (NCPE)

Publications

Sloand EM, Thompson BT

Propranolol-induced pulmonary edema and shock in a patient with pheochromocytoma.

Archives of internal medicine 1984 Jan;144;173-4 — 1984 Jan — 173-4

Auzépy P, Boukara N, Richard C, Giudicelli JF

[Acute poisoning caused by beta blockers in the adult. Apropos of 7 cases].

Annales de cardiologie et d'angeiologie 1983 Jun;32;253-8 — 1983 Jun — 253-8

Greenblatt DJ, Koch-Weser J

Adverse reactions to propranolol in hospitalized medical patients: a report from the Boston Collaborative Drug Surveillance Program.

American heart journal 1973 Oct;86;478-84 — 1973 Oct — 478-84

Desai SP, Pierce EC, Fleming TC

Severe hypertension, propranolol, and acute pulmonary edema.

Critical care medicine 1987 Aug;15;799-800 — 1987 Aug — 799-800