The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LV.bh

Imaging: Tumoral cavitation

Publications

Taniguchi M, Mori M, Sata N, Fujii H

[A Patient with Cavitated Pulmonary Metastases Treated with Regorafenib].

Gan to kagaku ryoho. Cancer & chemotherapy 2016 Jun;43;757-9 — 2016 Jun — 757-9

Kawasaki K, Hamamoto Y, Adachi M, Kanai T, Takaishi H

Early tumor cavitation with regorafenib in metastatic colorectal cancer: A case report.

Oncology letters 2016 Jan;11;231-233 — 2016 Jan — 231-233

Leuzzi G, Alessandrini G, Ferraresi V, Ferretti G, Forcella D, Facciolo F

Bilateral spontaneous pneumothorax and massive pneumomediastinum under Pazopanib therapy.

Thoracic cancer 2015 Jan;6;110-1 — 2015 Jan — 110-1