The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLVI.a

Pulmonary embolism - Venous thrombosis/thromboembolism

Publications

Li GC, Greenberg CS, Currie MS

Procainamide-induced lupus anticoagulants and thrombosis.

Southern medical journal 1988 Feb;81;262-4 — 1988 Feb — 262-4

Asherson RA, Zulman J, Hughes GR

Pulmonary thromboembolism associated with procainamide induced lupus syndrome and anticardiolipin antibodies.

Annals of the rheumatic diseases 1989 Mar;48;232-5 — 1989 Mar — 232-5