The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLV.a

Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

Publications

Kalomenidis I, Papiris S, Loukides S

Bilateral pleural effusions associated with pravastatin sodium treatment.

The European respiratory journal 2007 Nov;30;1022 — 2007 Nov — 1022

Liscoët-Loheac N, André N, Couturaud F, Chenu E, Quiot JJ, Leroyer C

[Hypersensitivity pneumonitis in a patient taking pravastatin].

Revue des maladies respiratoires 2001 Sep;18;426-8 — 2001 Sep — 426-8