The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.e

Organizing pneumonia pattern (an area or areas of consolidation on imaging)

Publications

Polverosi R, Maffesanti M, Dalpiaz G

Organizing pneumonia: typical and atypical HRCT patterns.

La Radiologia medica 2006 Mar;111;202-12 — 2006 Mar — 202-12

Camus P, Lombard JN, Perrichon M, Piard F, Guérin JC, Thivolet FB, Jeannin L

Bronchiolitis obliterans organising pneumonia in patients taking acebutolol or amiodarone.

Thorax 1989 Sep;44;711-5 — 1989 Sep — 711-5