The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LI.n

Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

Publications

Kitamura T, Fukamizu S, Hojo R, Hayashi T, Komiyama K, Tanabe Y, Tejima T, Sakurada H, Nishizaki M, Hiraoka M

Various morphologies of bidirectional ventricular tachycardia caused by aconite "Torikabuto" poisoning.

Journal of cardiology cases 2013 Feb;7;e42-e44 — 2013 Feb — e42-e44

Sheth S, Tan EC, Tan HH, Tay L

Herb-induced cardiotoxicity from accidental aconitine overdose.

Singapore medical journal 2015 Jul;56;e116-9 — 2015 Jul — e116-9