The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Airway hyperresponsiveness
Publications
Terzano C, Morano S, Ceccarelli D, Conti V, Paone G, Petroianni A, Graziani E, Carnovale A, Fallarino M, Gatti A, Mandosi E, Lenzi A
Effect of insulin on airway responsiveness in patients with type 2 diabetes mellitus: a cohort study.
The Journal of asthma : official journal of the Association for the Care of Asthma 2009 Sep;46;703-7 — 2009 Sep — 703-7