Back to drug

The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.m

ILD with a granulomatous component

Publications

Kuse N, Abe S, Kuribayashi H, Inomata M, Saito H, Fukuda Y, Gemma A

A case of vildagliptin-induced interstitial pneumonia.

Respiratory medicine case reports. 2016;18:10-3

Sada KE, Wada J, Morinaga H, Tuchimochi S, Uka M, Makino H

Sarcoid-like lung granulomas in a hemodialysis patient treated with a dipeptidyl peptidase-4 inhibitor.

Clinical kidney journal. 2014;7(2):182-5