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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

III.b

Pneumorenal syndrome (w/wo ANCAs)

Publications

Sharma R, Jain S, Kher V

ANCA-associated Goodpasture's syndrome in a patient with rheumatoid arthritis on penicillamine.

Indian journal of nephrology. 2012;22(1):45-7

Derk CT, Jimenez SA

Goodpasture-like syndrome induced by D-penicillamine in a patient with systemic sclerosis: report and review of the literature.

The Journal of rheumatology. 2003;30(7):1616-20

Bindi P, Gilson B, Aymard B, Noël LH, Wieslander J

Antiglomerular basement membrane glomerulonephritis following D-penicillamine-associated nephrotic syndrome.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 1997;12(2):325-7

Gaskin G, Thompson EM, Pusey CD

Goodpasture-like syndrome associated with anti-myeloperoxidase antibodies following penicillamine treatment.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 1995;10(10):1925-8

Peces R, Riera JR, Arboleya LR, López-Larrea C, Alvarez J

Goodpasture's syndrome in a patient receiving penicillamine and carbimazole.

Nephron. 1987;45(4):316-20

Bonan G, Caubarrere I, Beaufils H, Lucsko M, Aubert P

[Diffuse alveolar hemorrhage and severe glomerulonephritis induced by D-penicillamine. Apropos of a case report with review of the literature].

Therapie. 1986;41(4):297-8

Sternlieb I, Bennett B, Scheinberg IH

D-penicillamine induced Goodpasture's syndrome in Wilson's disease.

Annals of internal medicine. 1975;82(5):673-6