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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.c

Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

Publications

Souza CA, Müller NL, Johkoh T, Akira M

Drug-induced eosinophilic pneumonia: high-resolution CT findings in 14 patients.

AJR. American journal of roentgenology. 2006;186(2):368-73

WARRING FC Jr, HOWLETT KS Jr

Allergic reactions to para-aminosalicylic acid; report of seven cases, including one case of Löffler's syndrome.

American review of tuberculosis. 1952;65(3):235-49

MILLER FF, GREEN RA

Loeffler's syndrome due to paraaminosalicylic acid.

Diseases of the chest. 1962;42:100-3

KALINOWSKI SZ, LLOYD TW, MOYES EN

Complications in the chemotherapy of tuberculosis. A review with analysis of the experience of 3,148 patients.

The American review of respiratory disease. 1961;83:359-71

HOLMBOE AM

Lung infiltrations as a complication of PAS treatment.

Tubercle. 1958;39(3):169-71

WOLD DE, ZAHN DW

Allergic (Löffler's) pneumonitis occurring during antituberculous chemotherapy; report of three cases.

American review of tuberculosis. 1956;74(3):445-53

ATWELL RJ, PRIOR JA

Allergic pneumonitis during chemotherapy for tuberculosis: report of two cases due to paraaminosalicylic acid.

Annals of internal medicine. 1955;42(1):190-7

TUCHMAN H

Löffler's reaction to para-aminosalicylic acid.

American review of tuberculosis. 1954;70(1):171-5

Camus P, Piard F, Ashcroft T, Gal AA, Colby TV

The lung in inflammatory bowel disease.

Medicine. 1993;72(3):151-83