The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.w

Multiple organ dysfunction/failure (MODS/MOF)

Publications

Coopman V, De Leeuw M, Cordonnier J, Jacobs W

Suicidal death after injection of a castor bean extract (Ricinus communis L.).

Forensic science international 2009 Aug 10;189;e13-20 — 2009 Aug 10 — e13-20

Audi J, Belson M, Patel M, Schier J, Osterloh J

Ricin poisoning: a comprehensive review.

JAMA 2005 Nov 09;294;2342-51 — 2005 Nov 09 — 2342-51