The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.c

Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

Publications

Seigneur J, Trechot PF, Hubert J, Lamy P

Pulmonary complications of hormone treatment in prostate carcinoma.

Chest 1988 May;93;1106 — 1988 May — 1106

Pfitzenmeyer P, Foucher P, Piard F, Coudert B, Braud ML, Gabez P, Lacroix S, Mabille JP, Camus P

Nilutamide pneumonitis: a report on eight patients.

Thorax 1992 Aug;47;622-7 — 1992 Aug — 622-7