The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Fluid retention
Publications
Single premedication dose of dexamethasone 20 mg IV before docetaxel administration.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 2011 Sep;17;155-9 — 2011 Sep — 155-9
Capillary protein leak syndrome appears to explain fluid retention in cancer patients who receive docetaxel treatment.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998 Oct;16;3426-32 — 1998 Oct — 3426-32