The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XIX.a

Path: NSIP-cellular pattern (see also Ia, Ib)

Publications

Bayas A, Menacher M, Schwaiblmair M, Märkl B, Naumann M

Alemtuzumab-associated diffuse alveolar damage - a case report.

BMC neurology 2020 Sep 23;20;357 — 2020 Sep 23 — 357

Creelan B, Ferber A

A fatal case of alemtuzumab-associated interstitial pneumonitis.

American journal of therapeutics 2008 Jan-Feb;15;82-4 — 2008 Jan-Feb — 82-4