The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

L.h

Aspiration, aspiration pneumonia (w/wo demonstrable pharyngeal dysmotility)

Publications

Brancaleone P, Delefortrie Q, Descamps O, Weynand B, Vanbever R, Detry G

Lipoid Pneumonia Associated with Polyethylene Glycol Chronic Aspiration.

American journal of respiratory and critical care medicine 2023 Apr 15;207;e71-e72 — 2023 Apr 15 — e71-e72

Mosquera RA, McDonald M, Samuels C

Aspiration pneumonitis caused by polyethylene glycol-electrolyte solution treated with conservative management.

Case reports in pediatrics 2014;2014;872634 — 2014 — 872634