The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
DRES syndrome - DRESS-like reaction
Publications
Visceral involvements and long-term sequelae in drug-induced hypersensitivity syndrome.
The Medical clinics of North America. 2010;94(4):743-59, xi
Minocycline-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome with persistent myocarditis.
Journal of the American Academy of Dermatology. 2010;62(2):315-8
[Severe drug rash with eosinophilia and systemic symptoms after treatment with minocycline].
Revue des maladies respiratoires. 2007;24(7):892-5
Minocycline-induced central nervous system-pulmonary hypersensitivity syndrome.
International journal of dermatology. 2003;42(4):316-7
[Systemic reaction induced my minocycline treatment: a report of four patients and a review of the literature].
La Revue de medecine interne. 1999;20(10):869-74
Fever, lymphadenopathy, eosinophilia, lymphocytosis, hepatitis, and dermatitis: a severe adverse reaction to minocycline.
Journal of the American Academy of Dermatology. 1997;36(2 Pt 2):347-50
Serious adverse reactions induced by minocycline. Report of 13 patients and review of the literature.
Archives of dermatology. 1996;132(8):934-9