The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.l

Lung nodule or nodules

Publications

Kameya T, Morita T, Tanaka I, Koshida H, Igarachi Y, Horikami K, Nagai T, Kato M, Nanbu S

[A case of minocycline-induced hypersensitivity pneumonitis with radiographic finding of multiple nodules].

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 1994 Nov 10;83;1991-2 — 1994 Nov 10 — 1991-2

Piperno D, Donné C, Loire R, Cordier JF

Bronchiolitis obliterans organizing pneumonia associated with minocycline therapy: a possible cause.

The European respiratory journal 1995 Jun;8;1018-20 — 1995 Jun — 1018-20