The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIII.a

Bronchospasm - Wheezing - Asthma

Publications

Lawrence DS, Sahay JN, Chatterjee SS, Cruickshank JM

Asthma and beta-blockers.

European journal of clinical pharmacology 1982;22;501-9 — 1982 — 501-9

Lammers JW, Folgering HT, van Herwaarden CL

Respiratory tolerance of bisoprolol and metoprolol in asthmatic patients.

Journal of cardiovascular pharmacology 1986;8 Suppl 11;S69-73 — 1986 — S69-73