The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

II.a

Pulmonary edema, noncardiogenic (NCPE)

Publications

SCHOENFELD MR

ACUTE PULMONARY EDEMA CAUSED BY BARBITUATE POISONING. A CONSIDERATION OF ITS GENESIS AND THERAPY.

Angiology 1964 Oct;15;445-53 — 1964 Oct — 445-53

Gelb AF, Klein E

Hemodynamic and alveolar protein studies in noncardiac pulmonary edema.

The American review of respiratory disease 1976 Nov;114;831-5 — 1976 Nov — 831-5