The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

IV.a

Bronchospasm - Wheezing - Asthma

Publications

Scala E, Giani M, Pirrotta L, Guerra EC, De Pità O, Puddu P

Occupational asthma due to metoclopramide hydrochloride (MCPH).

International journal of immunopathology and pharmacology 2001 Sep-Dec;14;145-146 — 2001 Sep-Dec — 145-146

Chung MM, Chetty KG, Jerome D

Metoclopramide and asthma.

Annals of internal medicine 1985 Nov;103;809 — 1985 Nov — 809

Fujii M, Kiura K

[A case of asthma attack induced by high-dose metoclopramide].

Gan to kagaku ryoho. Cancer & chemotherapy 1986 Sep;13;2858-60 — 1986 Sep — 2858-60