The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.i

Hypersensitivity reaction (may manifest with fever and/or skin, throat or airway involvement)

Publications

DaVeiga SP, Liu X, Caruso K, Golubski S, Xu M, Lang DM

Systemic reactions associated with subcutaneous allergen immunotherapy: timing and risk assessment.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2011 Jun;106;533-537.e2 — 2011 Jun — 533-537.e2

Matloff SM, Bailit IW, Parks P, Madden N, Greineder DK

Systemic reactions to immunotherapy.

Allergy proceedings : the official journal of regional and state allergy societies 1993 Sep-Oct;14;347-50 — 1993 Sep-Oct — 347-50